Scientific Highlights


Day 1 : 2 September 2023 Saturday
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Session Type Speaker Moderator/ Session Chair Title of Presentation
13:25 13:30 0:05 Welcome William FOO    
Session 1: GI and Hepatobiliary
13:30 13:40 0:10 Presentation Johnny K S Lau Dr K O Lam FOLFOXIRI plus bevacizumab and atezolizumab as upfront treatment of unresectable metastatic colorectal cancer (mCRC): Updated and overall survival results of the phase II randomized AtezoTRIBE study.
13:40 13:50 0:10 Presentation K Yamazaki, Japan Efficacy of panitumumab in patients with left-sided disease, MSS/MSI-L, and RAS/BRAF WT: A biomarker study of the phase III PARADIGM trial.
13:50 14:00 0:10 Presentation Masanori Terashima, Japan ATTRACTION-5: A phase 3 study of nivolumab plus chemotherapy as postoperative adjuvant treatment for pathological stage III (pStage III) gastric or gastroesophageal junction (G/GEJ) cancer.
14:00 14:10 0:10 Presentation Eileen O'Reilly, USA Liposomal irinotecan + 5-fluorouracil/leucovorin + oxaliplatin (NALIRIFOX) versus nab-paclitaxel + gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma (mPDAC): 12- and 18-month survival rates from the phase 3 NAPOLI 3 trial.
14:10 14:20 0:10 Presentation Jianwei Zhang, China Long-term outcome of neoadjuvant mFOLFOX6 with or without radiation versus fluorouracil plus radiation for locally advanced rectal cancer: A multicenter, randomized phase III trial.
14:20 14:30 0:10 Presentation K O Lam PROSPECT: A randomized phase III trial of neoadjuvant chemoradiation versus neoadjuvant FOLFOX chemotherapy with selective use of chemoradiation, followed by total mesorectal excision (TME) for treatment of locally advanced rectal cancer (LARC) (Alliance N1048).
14:30 14:40 0:10 Presentation Thiery Conroy, France Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiation in patients with locally advanced rectal cancer: 7-year results of PRODIGE 23 phase III trial, a UNICANCER GI trial.
14:40 14:50 0:10 Presentation Masatoshi Kudo Efficacy, safety and patient reported outcomes (PROs) from the phase III IMbrave050 trial of adjuvant atezolizumab (atezo) + bevacizumab (bev) vs active surveillance in patients with hepatocellular carcinoma (HCC) at high risk of disease recurrence following resection or ablation.
14:50 15:05 0:15 Panel Discussion, Q&A     
Session 2: Lung Cancer
15:05 15:15 0:10 Presentation Yi-Long Wu, China Dr Oscar Chan Randomized phase 3 study of first-line AZD3759 (zorifertinib) versus gefitinib or erlotinib in EGFR-mutant (EGFRm+) non–small-cell lung cancer (NSCLC) with central nervous system (CNS) metastasis.
15:15 15:25 0:10 Presentation Yasushi Goto, Japan TROPION-Lung02: Datopotamab deruxtecan (Dato-DXd) plus pembrolizumab (pembro) with or without platinum chemotherapy (Pt-CT) in advanced non-small cell lung cancer (aNSCLC).
15:25 15:35 0:10 Presentation Oscar Chan OS survival analysis from the ADURA trial of adjuvant osimertinib in patients with resected EGFR-mut stage 1B-IIIA NSCLC
15:35 15:45 0:10 Presentation Quincy S. Chu, Canada IND227 phase III (P3) study of cisplatin/pemetrexed (CP) with or without pembrolizumab (Pembro) in patients (pts) with malignant pleural mesothelioma (PM): A CCTG, NCIN, and IFCT trial.
15:45 15:55 0:10 Presentation James Chih-Hsin Yang, China Pemetrexed and platinum with or without pembrolizumab for tyrosine kinase inhibitor (TKI)-resistant, EGFR-mutant, metastatic nonsquamous NSCLC: Phase 3 KEYNOTE-789 study.
15:55 16:05 0:10 Presentation Conrad Lee Tumor Treating Field (TTFields) therapy with standard of care (SOC) in metastatic non-small cell lung cancer (mNSCLC) following platinum failure: Randomized, phase 3 LUNAR study.
16:05 16:15 0:10 Presentation Heather Wakele, USA KEYNOTE-671: Randomized, double-blind, phase 3 study of pembrolizumab or placebo plus platinum-based chemotherapy followed by resection and pembrolizumab or placebo for early stage NSCLC.
16:15 16:30 0:15 Panel Discussion, Q&A     
Session 3: Head and Neck Cancer
16:30 16:40 0:10 Presentation David Johnson Prof Brigette Ma Results of the multicenter phase II FRAIL-IMMUNE trial evaluating the efficacy and safety of durvalumab combined with weekly paclitaxel carboplatin in first-line in patients (pts) with recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) not eligible for cisplatin-based therapies.
16:40 16:50 0:10 Presentation James Chow Neoadjuvant nivolumab, paclitaxel, and carboplatin followed by response-stratified chemoradiation in locoregionally advanced HPV negative head and neck squamous cell carcinoma (HNSCC): The DEPEND trial.
16:50 17:00 0:10 Presentation Dr. Liu Xu PD-1 blockade with Sintilimab plus induction chemotherapy and concurrent chemoradiotherapy (IC-CCRT) versus IC-CCRT in locoregionally-advanced nasopharyngeal carcinoma (LANPC): a multicenter, phase 3, randomized controlled trial (CONTINUUM)
17:00 17:15 0:15 Panel Discussion, Q&A     
 
Day 2 : 3 September 2023 Sunday
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Session Type Speaker Moderator/ Session Chair Title of Presentation
Session 4: Breast Cancer
10:00 10:10 0:10 Presentation Ann Chan Prof Roger Ngan Efficacy and safety results by age in monarche: Adjuvant abemaciclib combined with endocrine therapy (ET) in patients with HR+, HER2-, node-positive, high-risk early breast cancer (EBC).
10:10 10:20 0:10 Presentation Roland Leung Evaluation of PAM50 intrinsic subtypes and risk of recurrence (ROR) scores in premenopausal women with early-stage HR+ breast cancer: A secondary analysis of the SOFT trial.
10:20 10:30 0:10 Presentation Joanne Chiu Racial/ethnic differences in 21-gene recurrence score and survival among estrogen receptor-positive breast cancer patients.
10:30 10:40 0:10 Presentation Cynthia Yeung Second-line endocrine therapy (ET) with or without palbociclib (P) maintenance in patients (pts) with hormone receptor-positive (HR[+])/human epidermal growth factor receptor 2-negative (HER2[-]) advanced breast cancer (ABC): PALMIRA trial.
10:40 10:50 0:10 Presentation Sara Tolaney, USA Final overall survival (OS) analysis from the phase 3 TROPiCS-02 study of sacituzumab govitecan (SG) in patients (pts) with hormone receptor–positive/HER2-negative (HR+/HER2–) metastatic breast cancer (mBC).
10:50 11:00 0:10 Presentation NG Ting Ying Phase III NATALEE trial of ribociclib + endocrine therapy as adjuvant treatment in patients with HR+/HER2− early breast cancer.
11:00 11:10 0:10 Presentation  William FOO Effects of ovarian ablation or suppression on breast cancer recurrence and survival: Patient-level meta-analysis of 14,993 pre-menopausal women in 25 randomized trials.
11:10 11:20 0:10 Presentation Kenneth Li 3-year invasive disease-free survival (iDFS) of the strategy-based, randomized phase II PHERGain trial evaluating chemotherapy (CT) de-escalation in human epidermal growth factor receptor 2-positive (HER2[+]) early breast cancer (EBC).
11:20 11:35 0:15 Panel Discussion, Q&A     
11:35 12:20 0:45 GILEAD Sponsored Session Joline Lim Sacituzumab Govitecan – A new paradigm for metastatic breast cancer
Session 5 : Genitourinary Cancer — Kidney and Bladder | Prostate, Testicular and Penile
12:20 12:30 0:10 Presentation FY Cheung Dr FY Cheung TALAPRO-2: Phase 3 study of talazoparib (TALA) + enzalutamide (ENZA) versus placebo (PBO) + ENZA as first-line (1L) treatment for patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) harboring homologous recombination repair (HRR) gene alterations.
12:30 12:40 0:10 Presentation Martin Lam Efficacy and safety of atezolizumab plus cabozantinib vs cabozantinib alone after progression with prior immune checkpoint inhibitor (ICI) treatment in metastatic renal cell carcinoma (RCC): Primary PFS analysis from the phase 3, randomized, open-label CONTACT-03 study.
12:40 12:50 0:10 Presentation Darren Poon Prostate irradiation in men with de novo, low-volume, metastatic, castration-sensitive prostate cancer (mCSPC): Results of PEACE-1, a phase 3 randomized trial with a 2x2 design.
12:50 13:00 0:10 Presentation Angus Leung Pembrolizumab plus axitinib versus sunitinib as first-line therapy for advanced clear cell renal cell carcinoma: 5-year analysis of KEYNOTE-426.
13:00 13:15 0:15 Panel Discussion, Q&A     
Session 6: Gynaecologic Cancer
13:15 13:25 0:10 Presentation Philip Wu Dr William Foo KEYNOTE-826: Final overall survival results from a randomized, double-blind, phase 3 study of pembrolizumab + chemotherapy vs placebo + chemotherapy for first-line treatment of persistent, recurrent, or metastatic cervical cancer.
13:25 13:35 0:10 Presentation Winnie Yip Dostarlimab for primary advanced or recurrent (A/R) endometrial cancer (EC): Outcomes by blinded independent central review (BICR) of the RUBY trial (ENGOT-EN6-NSGO/GOG-3031/RUBY).
13:35 13:45 0:10 Presentation K Y Tse Final survival analysis of the phase III OVHIPEC-1 trial of hyperthermic intraperitoneal chemotherapy in ovarian cancer after ten year follow-up.
13:45 14:00 0:15 Panel Discussion, Q&A     
14:00 14:15 0:15 CLOSING REMARKS




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